The Virtual USB Bus Error 39 in Mastercam versions from X7 through 2022 is typically caused by a Windows security feature called Core Isolation (Memory Integrity), which prevents unsigned or older drivers from loading. Primary Fix: Disable Memory Integrity
This is the most common solution for modern Windows 10 and 11 systems where the driver is blocked by security protocols.
Open Windows Security: Search for "Windows Security" in your Start menu.
Navigate to Device Security: Select the Device security tab on the left-hand menu.
Core Isolation Details: Click the link for Core isolation details.
Toggle Memory Integrity: Switch the Memory integrity setting to Off.
Restart: Reboot your computer to apply the changes. The driver should now load without Error 39. Secondary Fix: Windows Registry (HVCI Disable)
If the toggle is greyed out or does not resolve the issue, you can disable it via the Registry Editor.
Path: HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\DeviceGuard\Scenarios\HypervisorEnforcedCodeIntegrity Action: Set the Enabled DWORD value to 0. Restart: Reboot your PC after closing the editor. Advanced Troubleshooting
If the error persists after disabling Core Isolation, try these additional methods: How to Fix USB Error Code 39 In Windows 10/8/7 [Tutorial] mastercam x72022 virtual usb bus error 39 fix
Uninstall the broken driver
Clean registry entries (use with care)
Win + R, type regedit.HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Enum\USB\HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Class\36FC9E60-C465-11CF-8056-444553540000UpperFilters or LowerFilters referring to the virtual bus.Reinstall the virtual USB driver manually
vusbbus.inf, vusbbus.sys)..inf file.Disable driver signature enforcement (if on Windows 10/11)
Prevent Windows from auto-updating the driver
gpedit.msc (Pro/Enterprise) or wushowhide.diagcab to block automatic driver updates for that specific device.Windows 10/11 blocks unsigned kernel-mode drivers by default. Older Mastercam virtual bus drivers (pre-2020) often lack valid signatures.
Steps:
Note: This must be repeated after every Windows update or major reboot. For a permanent fix, see Fix 7 (Test Mode).
Before proceeding:
regedit).Note for Mastercam 2022 users: Version 2022 uses CodeMeter (Wibu) for licensing, not the Virtual USB Bus. If you see Error 39 with 2022, you are likely running an older HASP-dependent legacy installer or a mixed license environment. The fix below still applies.
dism /online /export-driver /destination:D:\DriverBackupCorrupted driver files are the #1 cause. Here’s how to force a clean reinstallation:
Download the latest driver pack for your Mastercam version:
Uninstall existing driver:
Clean driver remnants:
pnputil /delete-driver oem*.inf /uninstall /force
C:\Windows\System32\drivers and delete vusbbus.sys, hardlock.sys, or cmudbus.sys if present.Reinstall fresh:
CodeMeterRuntime.exe or HASP_License_Manager.exe) as Administrator.Even after uninstalling, old driver files may linger.
Open File Explorer and navigate to:
C:\Windows\System32\drivers\
Look for and delete (or rename to .OLD) the following files if they exist: The Virtual USB Bus Error 39 in Mastercam
hardlock.syshasplms.sysaksdf.sysaksusb.sysvusbbus.sys (This is the main Virtual USB Bus driver)Also check:
C:\Windows\SysWOW64\drivers\
(Delete the same files if found).
Before diving into advanced fixes, run these quick checks:
If the error persists, proceed step-by-step.
The Virtual USB Bus driver (vusbbus.sys) is test-signed. Windows blocks it unless test signing is on.
How to enable:
bcdedit /set testsigning on
After restart, you'll see "Test Mode" in the lower-right corner of the desktop. That's normal.
Verification:
Open Device Manager → System devices → Virtual USB Bus (still showing error?). If yes, proceed to Step 2.
To revert later (after successful license detection): Most effective fix (step by step)
bcdedit /set testsigning off